SNAP-8 is a synthetic octapeptide designed as an extension of SNAP-25–derived peptide fragments. In biochemical and cellular research systems, SNAP-8 is studied for its interaction with components of the SNARE complex involved in vesicle fusion and neurotransmitter release.
Experimental investigations examine peptide–protein interactions, modulation of synaptic signalling, and comparative activity relative to shorter SNAP-derived peptides. Observed effects are dependent on experimental design, concentration, and model system and are used to explore peptide-mediated signalling mechanisms rather than defined biological or physiological outcomes.
Applications in Research
• Investigation of SNARE-complex interactions and synaptic signalling
• Study of peptide effects on neurotransmitter release mechanisms
• Use as a reference peptide in neuromuscular signalling research
Specifications Summary
Purity: ≥ 99% (HPLC, typical)
Appearance: White to off-white lyophilised powder
Peptide Type: Synthetic octapeptide
Molecular Weight: 1075.16 g/mol
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 10 mg
Precautions & Notes
• Experimental behaviour is dependent on concentration and model system
• Peptide stability may be influenced by pH and buffer composition
• Intended strictly for laboratory research use; not for human or veterinary application
References
PubChem. Acetyl Octapeptide-3 (SNAP-8) compound summary.
https://pubchem.ncbi.nlm.nih.gov/compound/Acetyl-octapeptide-3
NamSiang. SNAP-8 peptide (Acetyl Octapeptide-3) research and mechanism overview.
https://namsiang.com/en/product/lptr-077-es-99/
Advanced ChemTech. Acetyl Octapeptide-3 (SNAP-8) peptide technical listing (CAS 868844-74-0).
https://advancedchemtech.com/product/acetyl-octapeptide-3-snap-8/
MolChanges. SNAP-8 peptide mechanism and SNARE complex interaction overview.
https://molchanges.com/snap-8
Keywords: SNAP-8, SNARE-modulating peptide, Synthetic octapeptide
