Pinealon is a short synthetic tripeptide originally identified through research into pineal gland–derived regulatory peptides. It has been investigated in neuronal cell models for its role in cellular stress resistance and the regulation of gene expression associated with circadian biology.
In biochemical and cellular research systems, Pinealon has been studied for its influence on neuronal survival pathways, oxidative stress modulation, and peptide–DNA interactions. Observed molecular responses are dependent on experimental design, concentration, and model system, and are used to explore peptide-mediated regulatory mechanisms rather than defined physiological outcomes.
Applications in Research
• Investigation of cytoprotective peptide signalling in neuronal cell models
• Study of pineal-derived peptide regulation and circadian-associated pathways
• In vitro models examining cellular stress resistance mechanisms
• Use as a reference compound in short regulatory peptide research
Specifications Summary
Purity: ≥ 99% (HPLC)
Appearance: White to off-white lyophilised powder
Peptide Type: Synthetic pineal regulatory tripeptide
Molecular Weight: 418.407 g/mol
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 20 mg
Precautions & Notes
• Experimental behaviour of Pinealon is influenced by concentration, exposure duration, and model system
• Short regulatory peptides may exhibit rapid degradation in some in vitro systems
• Buffer composition and pH may affect peptide stability
• Appropriate controls are recommended for mechanistic studies
• Intended strictly for laboratory research use; not for human or veterinary application
References
Epitalon (pineal tetrapeptide) — molecular and biological overview.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11943447/
Keywords: Pinealon, Pineal Peptide, Synthetic Tripeptide, Regulatory Peptide
