Semax is a synthetic peptide that is an analog of adrenocorticotropic hormone (ACTH). It has been studied for its neuroprotective, cognitive-enhancing, and antidepressant effects. Semax stimulates the release of brain-derived neurotrophic factor (BDNF), a protein that promotes neuron growth and survival, and modulates neurotransmitter levels including dopamine, serotonin, and norepinephrine. It offers nootropic, neuroprotective, and neurorestorative benefits.
Molecular Formula: C₁₄₆H₂₃₆N₄₀O₄₃S
Molecular Weight: 3146.2 g/mol
Purity: 99%
For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, and must not be misused in any way that contravenes MHRA regulations or applicable laws.
Semax is a synthetic peptide that is an analog of adrenocorticotropic hormone (ACTH). It has been studied for its neuroprotective, cognitive-enhancing, and antidepressant effects. Semax stimulates the release of brain-derived neurotrophic factor (BDNF), a protein that promotes neuron growth and survival, and modulates neurotransmitter levels including dopamine, serotonin, and norepinephrine. It offers nootropic, neuroprotective, and neurorestorative benefits.
Benefits
Memory enhancement: Participants using Semax made 31% more correct responses than the control group on memory tests
Neu
oprotection: Shields neurons from stroke, trauma, or neurodegenerative disease damage
Antidepressant effects: Reduces anxiety and depression in animal studies
Supports neuron survival and promotes synaptic growth and neuroplasticity
Helps neurons adapt to injury or environmental change
Protects the optic nerve and may be helpful for related disorders
Improves trophic supply of the brain (supports brain network connectivity)
May help manage ADHD symptoms
Inhibits enzymes that degrade enkephalins and regulatory peptides
May support recovery from opioid or alcohol withdrawal
Shows improvement in non-proliferative diabetic neuropathy
Potential for pain relief
Possible Side Effects
Headache
Mild dizziness or light-headedness
Very rare risk of slight increase in blood sugar levels
Injection site reaction (redness, swelling, and/or itching)
Warnings and Precautions
Semax modulates central nervous system signaling pathways, including dopaminergic, serotonergic, and neurotrophic (e.g. BDNF-related) mechanisms. Use caution in individuals with a history of:
Anxiety disorders
Panic disorder
Bipolar disorder (including hypomania or mania)
Psychotic disorders or schizophrenia
Potential adverse neuropsychiatric effects may include agitation, irritability, restlessness, or insomnia. Discontinue use if clinically significant psychiatric symptoms emerge or worsen.
Contraindications
Do not use if you determine that you are hypersensitive to Semax- this is an indication of an allergic reaction
Do not use if pregnant or breastfeeding
Avoid in individuals with endocrine instability
Use caution if you have a severe psychiatric disorder (particularly active psychosis, manic episodes, or uncontrolled anxiety)- the stimulatory/neuroactive effects could worsen mood/psychiatric state
Safety profile is not well established in children and pediatric use should be avoided
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