Kisspeptin-10 10mg
Kisspeptin-10, a neuropeptide regulating GnRH release, is central to reproductive function research. Studied for roles in fertility, puberty onset, and sexual health, it also provides insights into hormone therapy, reproductive medicine, and the metabolic–reproductive link in experimental models.
- Molecular Formula: C₁₀H₁₆N₆O₄
- Molecular Weight:28 g/mol
- Purity: ≥98%
- Sequence: Tyr-Asn-Trp-Asn-Pro-Gln-Pro-Gln-Gly-Leu
For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, and must not be misused in any way that contravenes MHRA regulations or applicable laws.
Details
Kisspeptin is a neuropeptide produced by the hypothalamus, a part of the brain that controls the release of several important hormones in the body including gonadotropin-releasing hormone (GnRh), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). Kisspeptin plays a major role in reproductive function in both men and women, secretion of aldosterone (which regulates water and salt balance), tumor suppression, and kidney function. Kisspeptin was originally named Metastin, a direct reflection of its ability to prevent the spread of cancer.
Benefits
- Increases testosterone levels by stimulating the release of LH, which in turn stimulates Leydig cells to produce testosterone
- Boosts immunity
- Regulates reproductive hormone release
- Enhances fertility
- Aids metabolic function and promotes weight loss
- Prevents wrinkles and signs of aging
- Boosts cognitive function
- Increases liver antioxidants
- Temporarily increases oxytocin
- Boosts insulin secretion
- Possible remedy for erectile dysfunction
- Treats fertility disorders
- Reacts with sexual stimuli and affects hormonal pulse frequency
- Lowers risk of heart disease
- Plays a role in puberty onset
- Potential treatment for polycystic ovarian syndrome
Kisspeptin and Non-Alcoholic Fatty Liver Disease
Kisspeptin helps reduce fat already deposited in the liver and prevents its initial accumulation, making it beneficial for managing early-stage NAFLD.
How It Works
- Binds to G-protein coupled receptors
- Stimulates GnRH → stimulates LH, FSH, and sex steroid secretion
- Increases testosterone, estrogen, progesterone
- Increases HCG-stimulated progesterone secretion in luteal cells
Alternative to HCG
Kisspeptin may serve as a natural alternative to HCG for maintaining fertility and hormonal balance in testosterone therapy. It stimulates LH and testosterone production, helping restore the HPG axis.
Possible Side Effects (Very uncommon)
- Diarrhea
- Sweating
- Headache
- Hot flushes
- Dizziness
- Shortened menstrual cycle
- Altered metabolism due to decreased food intake
Dosing Considerations
- Effects last up to 24 hours after injection
- LH/testosterone peak 45–60 minutes post-dose
- Works best when fasted: fasting increases LH response 5–6x compared to fed state
- Best results with 1mcg/kg bodyweight
- Desensitization can occur if used too frequently
- Optimal frequency: 2x/week
Stacking Suggestions
Kisspeptin can be effectively combined with:
- HCG – For enhanced stimulation of LH and FSH
- Tesamorelin or CJC-1295/Ipamorelin – Synergistic hormone support and fat loss
- BPC-157 or TB-500 – Tissue repair and injury recovery
- AOD-9604 – Amplifies fat loss effects
- Tirzepatide or Semaglutide – Improves insulin sensitivity and body composition
For libido and fertility stacks:
Kisspeptin + PT-141 + HCG for synergistic effects on sex drive, hormone balance, and fertility